yes, I have used it....I have literally used everything dermatologists can prescribe, and I tried this when it first came out about 5 years ago. I hated it. It didn't work and it left scars. Like I said, I have used everything..and nothing left scars but Proactive. And not just red scars, I'm talking holes in my face. It's just one, but, it's on my cheek and about the size of a pencil eraser. As soon as I noticed it, I stopped using it. Went back to what the Derm prescribed. I hope you have better luck. Everyone's face and skin is different, so, what works for me, might not work for you and vise versa.
My younger son has used ProActiv, and he seems ok with it. The older boy had a tougher time with acne and went through two courses of Accutane, and that did the trick. Accutane is serious stuff and does a number on your liver and blood chemistry. It's expensive (Insurance paid it.), and it requires regular lab tests and monitoring by a doctor.
Have bicycle, will ride. Finished 2012 with 10,089 miles, 683 hours, and 482,000 feet of elevation gain. 2013: 201 rides, 8171 miles, 544 hours, 480K feet.
2014 so far: 7846 miles, 451,000 feet
that's actually one thing I haven't tried. They wanted to put me on Accutane, and after seeing that HUGE book they call a consent form, I changed my mind. My face isn't THAT bad, I can live with it. I heard it works wonders though. That you never have to worry about your face again.