We went a few years ago and stayed at the Comfort Inn Hotel Circle. It was right off the highway so was fairly easy access to Old Town, Seaport Village, Downtown, the zoo, and Sea World. We are out of towners but found that with the map we received from the car rental company - everything was easily accessible and the rate was $75/night. We checked the rate through expedia, but booked directly through the hotel. They were great. The rate went down on expedia a week before we left. i called the hotel and they adjusted our rate to match that one. Had a nice all-day breakfast diner on the property as well.