Imagine a World Grand Prix attraction with both indoor and outdoor elements. They can build smaller segments of each of the race tracks from Tokyo, London, Monoco, etc. Maybe have have it be randomized so that you don't experience the same locales all the time but the finish will be the most amazing section of track there is. I think that would be a great replacement for "Radiator Springs Racers".
If they want to incorporate Mater having a bomb in his engine into the ride, I don't think I'd be against it.
I see this as more likely, as it would be exportable to Tokyo and Paris. Jungle Race? What the heck? Let's keep the theme to Radiator Springs or someplace with a Grand Prix.